Health & Physiology
Writing cell memory: how Histones play a role in Epigenetic Memory
Expression of a correct set of genes at the right time is crucial for cells to maintain their cell-type specific function. Epigenetic cell memory supports maintenance of such gene expression programs, with specific chromatin states regulating which genes to express or to keep silent. Chromatin... click to read more
How HIV-infected cells use immune checkpoints to evade the human immune system
About 38 million people live with Human Immunodeficiency Virus (HIV) worldwide and hopes for a significant reduction of new transmissions have only partially materialized. In contrast to other infectious diseases that can be readily cured with short-term antimicrobial treatment, HIV-1 infection remains incurable and requires... click to read more
Age-induced unsealing of the "Pandora's box": resurrection of endogenous retroviruses
Human evolution is like a tightrope walker with viruses – in a delicate balance. Endogenous retroviruses (ERVs), once part of ancient retroviral infections, are now permanently fixed in our genome. Most of them, including human ERVs (HERVs), like landmines buried in the past, accumulate mutations... click to read more
Low and Mighty: How Low-Affinity Antibodies Boost Cancer Immunotherapy
Our body is constantly guarded by our immune system, which defends us from external threats like viruses and bacteria, and even internal rogue cells that can become cancerous. Antibodies, which are special proteins in our bodies, play a key role in this defence. They work... click to read more
Mathematical modeling and tumor avatars: What’s the link?
Illustration realized in the framework of a collaboration between the Image/Recit option of the HEAD (Haute École d'Art et de Design) - Genève and the Faculty of Sciences of the University of Geneva.
Colorectal cancer figures among the most common and deadly cancers worldwide. With current... click to read more
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